During the conceptual stage of process design, the experimental work todetermine the reaction parameters is often carried out independently from thesimulation work used to develop the conceptual process. The result of thisdisconnect is that the optimal process may remain undiscovered, since theprocess design engineer is constrained by the reaction conditions originallystudied in the laboratory. By utilizing a methodology for integrating the processdevelopment with the laboratory experiments at the earliest stages, the processdesigner can ensure that the laboratory data is gathered only for economicallyviable and technically feasible process conditions. The methodology isillustrated through a case study on dehydration of bio-based glycerol.
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