Novel polymeric micellar drug delivery system with pH-controlled release of doxorubicin

机译：pH控制的阿霉素释放的新型聚合物胶束药物递送系统

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A novel polymeric micellar pH-sensitive system fordelivery of doxorubicin (DOX) with DOX bound viahydrolytically degradable hydrazone bond is described. Inaqueous buffers DOX was released faster at pH 5.0 thanat pH 7.4. DOX release was folloved by micelledisintegration and polymer dissolution.

机译：一种新型的聚合物胶束pH敏感系统，用于通过DOX结合的阿霉素（DOX）的递送描述了可水解降解的bond键。在水性缓冲液DOX在pH 5.0下的释放速度快于在pH 7.4下。 DOX释放受到胶束的追捧崩解和聚合物溶解。

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《Annual meeting exposition of the Controlled Release Society》|2005年|1-2|共2页
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Martin Hruby; Cestmir Konak; Karel Ulbrich;
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中图分类药学;
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1. Polymeric micellar pH-sensitive drug delivery system for doxorubicin [J] . Hruby M, Konak C, Ulbrich K Journal of Controlled Release: Official Journal of the Controlled Release Society . 2005,第1期

机译：阿霉素的聚合物胶束pH敏感药物递送系统
2. Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release [J] . Chytil Petr, Sirova Milada, Kudlacova Julia, Molecular pharmaceutics . 2018,第9期

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3. Coadsorption of Doxorubicin and Selected Dyes on Carbon Nanotubes. Theoretical Investigation of Potential Application as a pH-Controlled Drug Delivery System [J] . Panczyk Tomasz, Wolski Pawel, Lajtar Leszek Langmuir: The ACS Journal of Surfaces and Colloids . 2016,第19期

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4. Reduction the Initial-Burst Release of Doxorubicin from Polymeric Depot as a Local Drug Delivery System for Cancer Treatment [C] . Chitinart Thedrattanawong, Chalaisorn Thanapongpibul, Pinunta Nittayacharn, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：减少阿霉素从多聚体库的初次释放作为一种用于癌症治疗的局部药物递送系统
5. Polymeric drug delivery systems: Lidocaine microspheres for prolonged and localized in vivo anesthetic effects and light-induced drug release from polymeric device mediated by bacteriorhodopsin. [D] . Chen, Pen-Chung. 2004

机译：聚合物药物递送系统：利多卡因微球可延长和定位体内麻醉作用，并由细菌视紫红质介导的光诱导药物从聚合物装置中释放。
6. Bicomponent polymeric micelles for pH-controlled delivery of doxorubicin [O] . Chunyun Wang, Peilan Qi, Yan Lu, 2020

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7. Influence of Drug Lipophilicity on Drug Release from Sclera After Iontophoretic Delivery of Mixed Micellar Carrier System to Human Sclera [O] . Poonam Chopra, Jinsong Hao, S. Kevin Li 2013

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Novel polymeric micellar drug delivery system with pH-controlled release of doxorubicin

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