NON-INVASIVE ASSESSMENT OF CUTANEOUS SIDE EFFECT IN TRANSDERMAL IONTOPHORETIC DELIVERY WITH SURFACTANT PRETREATMENT

机译：表面活性剂预处理对皮下离子光化学传递的同时副作用的无创评估

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The primary aim of present study is to investigate local skin side effects of combined surfactant pretreatment and iontophoresis at a current density of 0.25 mA/cm~2 on human skin in vivo. After 3 hours of iontophoresis no changes in skin barrier and no clinically meaningful irritation were observed.

机译：本研究的主要目的是研究在0.25 mA / cm〜2的电流密度下，表面活性剂预处理和离子电渗疗法相结合的局部皮肤副作用。离子电渗疗法3小时后，皮肤屏障没有变化，也没有观察到具有临床意义的刺激性。

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来源
《Proceedings of the 29th Annual Meeting of the Controlled Release Society》|2002年|p.1135-1136|共2页
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作者
Gai-Ling Li; T. van der Steeg; M. Danhof; J. A. Bouwstra;
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正文语种
中图分类化学工业;
关键词
iontophoresis; skin barrier function; skin irritation; surfactant suspension;

机译：离子电渗疗法;皮肤屏障功能;皮肤刺激;表面活性剂悬浮液;

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专利

1. Transdermal iontophoretic delivery of apomorphine in patients improved by surfactant formulation pretreatment [J] . Li GL, de Vries JJ, van Steeg TJ, Journal of Controlled Release: Official Journal of the Controlled Release Society . 2005,第1a3期

机译：表面活性剂制剂预处理改善了阿扑吗啡的经皮离子电渗疗法
2. Pretreatment with a water-based surfactant formulation affects transdermal iontophoretic delivery of R-apomorphine in vitro. [J] . Li GL, Danhof M, Frederik PM, Pharmaceutical research . 2003,第4期

机译：水性表面活性剂制剂的预处理会影响R-阿扑吗啡的体外透皮离子电渗传递。
3. Controlled non-invasive transdermal iontophoretic delivery of zolmitriptan hydrochloride in vitro and in vivo. [J] . Patel SR, Zhong H, Sharma A European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2009,第2期

机译：盐酸佐米曲普坦的体外和体内控制性非侵入性透皮离子电渗疗法。
4. NON-INVASIVE ASSESSMENT OF CUTANEOUS SIDE EFFECT IN TRANSDERMAL IONTOPHORETIC DELIVERY WITH SURFACTANT PRETREATMENT [C] . Gai-Ling Li, T. van der Steeg, M. Danhof, Annual meeting of the Controlled Release Society . 2002

机译：用表面活性剂预处理的透皮离子电渗递送中皮肤副作用的非侵入性评估
5. Gemini cationic surfactant-based delivery systems for non-invasive cutaneous gene therapy. [D] . Badea, Ildiko. 2006

机译：基于双子阳离子表面活性剂的输送系统，用于非侵入性皮肤基因治疗。
6. Iontophoretic Transdermal Delivery of Human Growth Hormone (hGH) and the Combination Effect of a New Type Microneedle Tappy Tok Tok® [O] . Gyubin Noh, Taekwang Keum, Jo-Eun Seo, 2018

机译：人类生长激素（hGH）的离子电渗透皮递送和新型微针Tappy TokTok®的联合作用
7. Enhanced transdermal delivery of luteolin via non-ionic surfactant-based vesicle: quality evaluation and anti-arthritic assessment [O] . Lubna Abidin, Mohammed Mujeeb, Syed Sarim Imam, 2014

机译：通过非离子表面活性剂的囊泡增强叶绿素的透皮递送：质量评价和抗关关节炎评估
8. Non-invasive Transdermal Two-dimensional Mapping of Cutaneous Oxygenation with Rapid-drying Liquid Bandage. [R] . Li, Z., Roussakis, E., Koolen, P. G., 2014

机译：快速干燥液绷带皮肤氧合无创透皮二维定位。

NON-INVASIVE ASSESSMENT OF CUTANEOUS SIDE EFFECT IN TRANSDERMAL IONTOPHORETIC DELIVERY WITH SURFACTANT PRETREATMENT

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