RELIABILITY OF REPEATED DOSES OF TECHNOSPHERE~(TM)/INSULIN VIA THE PULMONARY AND SUBCUTANEOUS ROUTES

摘要

Repeated dose variability of pulmonary delivered Technosphere~(TM)/insulin vs. subcutaneously administered regular human insulin was determined in a clinical trial with nine Type 2 diabetics. Each patient was given three doses of each formulation one week apart. The CV% of repeated pulmonary administration was 19% while subcutaneous was 35%.