One of the most relevant problems of using optical fiber sensors in real-world environments is surface fouling, that is, the cumulative build-up of undesirable material on the working surface of the sensor. The present paper presents the results of tests of anti-biofouling coated fiber optic probes for reflectance spectroscopy in blood-simulating 'foul' media, namely Bovine Serum Albumin (BSA) and Fibrinogen. The anti-biofouling coating was a cross-linkable polymer with silane functionality, to improve adhesion to silica-containing substrates.
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