Non-invasive Wearable System for Hypoglycemia Detection: A Proof of Concept User-Centered Design Process

摘要

About 425 million adults around the world were living with diabetes in 2017. A relevant condition called Hypoglycemia is characterized by a dangerous low level of blood sugar that could be fatal to diabetic pa-tients. Continuous glucose monitoring systems (CGMS) are the most popular commercially available tech-nology for detecting diabetic hypoglycemia. However, CGMSs are invasive, costly, and not user-centric thereby not sustainable for diabetes management. This paper documents our initial efforts in designing an inexpensive, non-invasive, wearable physiological tremor sensory system to detect the onset of hypogly-cemic events of diabetic patients. The design cycle briefly presented here includes: 1) determination of sys-tem (technology and user) requirements, 2) development of the tremor detection prototype, and 3) testing and validation of the system in non-clinical and clinical settings using human factors, data analytics, and biomedical sciences techniques and approaches.