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An Implantable Epiretinal Vision Prosthesis for Retinitis Pigmentosa Patients

机译:色素性视网膜炎患者的植入式视网膜前视假体

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Retinal implants are an important neuro-prosthetical approach to restore vision in patients that are blind due to photoreceptor loss from retinitis pigmentosa. There are two main approaches. One is the subretinal implant, which is intented to be implanted at the level of the degenerated photoreceptors. The second approach is the epiretinal implant, whose stimulation electrodes are favourably placed from the vitreous side onto the retina of an eye. In this, visual information is captured with an external camera, processed and transmitted to a retinal stimulator that is secured intraocularly and whose electrodes stimulate retinal ganglion cells. As with most electrical prostheses advances are often related to advances in science and technology. Of equal importance are pre-clinical studies and surgical aspects of being able to implant such devices. Recently, the German EpiRet group implanted and tested their epiretinal vision prosthesis in blind human volunteers suffering from retinitis pigmentosa. We present implant's design and results of a clinical study to demonstrate the function and the applicability of the EpiRet vision prosthesis.
机译:视网膜植入物是一种重要的神经修复方法,可以恢复因色素性视网膜炎导致感光器丧失而失明的患者的视力。主要有两种方法。一种是视网膜下植入物,其目的是在退化的感光体水平上进行植入。第二种方法是前视网膜植入物,其刺激电极从玻璃体一侧有利地放置在眼睛的视网膜上。在这种情况下,视觉信息由外部摄像机捕获,进行处理并传输到固定在眼内的视网膜刺激器,其电极刺激视网膜神经节细胞。与大多数电子假体一样,进步通常与科学技术的进步有关。同样重要的是能够植入此类设备的临床前研究和外科方面。最近,德国EpiRet小组在患有色素性视网膜炎的盲人志愿者中植入并测试了他们的视网膜前视假体。我们介绍植入物的设计和临床研究结果,以证明EpiRet视觉假体的功能和适用性。

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