Power output uniformity and power output capabilities of a guidewire-compatible cylindrical light-diffusing catheter

摘要

Cardiovascular Photodynamic Therapy requires the uniform application of laser energy over the length of an atherosclerotic lesion, thus ensuring equal treatment to all parts of the lesion. The total amount of laser energy delivered to the lesion also affects the results of the treatment. Uniform light distribution both radially and axially of a cylindrical diffuser during Photodynamic Therapy prevents miscalculated dosimetry and uneven treatment. Maximizing the amount of laser power delivered to the cylindrical diffuser tip (without inducing temperature elevation) minimizes the exposure time thus reducing the overall treatment time. Power output uniformity and power output capabilities are thus crucial factors in the design of a cardiovascular cylindrical diffuser. This paper will discuss the output characteristics and performance of six guidewire compatible cylindrical diffusers. Each diffuser consists of an array of fiber optics surrounding an inner guidewire lumen. This assembly is covered by an outer sheath. The fibers launch into an elastomer which contains a scattering medium. In this way a light diffusing tip is created. The total length of the fiber system is 3.0 meters. The total length of the difffuser tip is 2.0 cm.