Pathway logic helping biologists understand and organize pathway information

摘要

Pathway Logic is an application of techniques from formal methods to the modeling and analysis of signal transduction networks in mammalian cells. These signaling network models are developed using Maude, a symbolic language founded on rewriting logic. Network elements (reactions) are represented as rewrite rules. Models can be queried (analyzed) using the execution, search and model-checking tools of the Maude system. Collections of rules and initial states of interest form a novel kind of database where a biologist can record results of both curation and experiments.