An image computing system for the estimation and reconstruction of diffuse volume of an anti-cancer drug in liver tumours

摘要

Presents a medical image computing system which has been designed to extract and analyze quantitative information from a spatial sequence of CT (computed tomography) images. In particular, it has been applied to the quantitation and 3D reconstruction of the diffuse pattern of a radio-opaque anti-cancer drug, lipiodol-doxorubicin, in hepatocellular carcinoma. The PC-based system computes quantitative measures which can be used to assess the effectiveness of the chemotherapeutic treatment and to study the histology of the tumour. The system can provide a visualization of the tumour volume and quantification of drug absorption using 3D surface reconstruction and graphics techniques.