The impact of laser irradiation during antimicrobial photodynamic therapy in an artificial biofilm model

摘要

The aim of the study was to assess the impact of laser irradiation during antimicrobialrnphotodynamic therapy.rnTest chambers containing each a salivary pellicle layer and a Stretococcus mutans culturernwere analyzed using confocal laser microscopy after adding a photosensitizer. Half of thernchambers were irradiated with a diode laser.rnComparing baseline fluorescence with the values after laser irradiation, a decrease ofrnfluorescence could be observed. The non-irradiated group showed a slight increase ofrnfluorescence.rnThe present study indicates that laser irradiation is an essential part to reduce bacteria byrnantimicrobial photodynamic therapy.