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Optical properties of nasal septum cartilage

机译:鼻中隔软骨的光学特性

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Abstract: Optical parameters (scattering coefficient s, absorption coefficient k and scattering anisotropy coefficient g) of hyaline cartilage were studied for the first time. Optical properties of human and pig nasal septum cartilage, and of bovine ear cartilage were examined using a spectrophotometer with an integrating sphere, and an Optical Multi-Channel Analyser. We measured total transmission T$-t$/, total reflection R$-t$/, and on-axis transmission T$-a$/ for light propagating through cartilage sample, over the visible spectral range (14000 - 28000 cm$+$MIN@1$/). It is shown that transmission and reflection spectra of human, pig and bovine cartilage are rather similar. It allows us to conclude that the pig cartilage can be used for in-vivo studies instead of human cartilage. The data obtained were treated by means of the one-dimensional diffusion approximation solution of the optical transport equation. We have found scattering coefficient s, absorption coefficient k and scattering anisotropy coefficient g by the iterative comparison of measured and calculated T$-t$/, R$-t$/ and T$-a$/ values for human and pig cartilage. We found, in particular, that for 500 nm irradiation s equals 37,6 plus or minus 3.5 cm$+$MIN@1$/, g equals 0,56 plus or minus 0.05, k approximately equals 0,5 plus or minus 0.3 cm$+$MIN@1$/. The above data were used in Monte Carlo simulation for spatial intensity profile of light scattered by a cartilage sample. The computed profile was very similar to the profile measured using an Optical Multi-Channel Analyzer (OMA). !6
机译:摘要:首次研究了透明软骨的光学参数(散射系数s,吸收系数k和散射各向异性系数g)。使用带积分球的分光光度计和光学多通道分析仪检查人和猪鼻中隔软骨和牛耳软骨的光学特性。我们测量了可见光谱范围(14000-28000 cm $ +)中通过软骨样品传​​播的光的总透射率T $ -t $ /,总反射率R $ -t $ /和轴上透射率T $ -a $ / $ MIN @ 1 $ /)。结果表明,人,猪和牛软骨的透射和反射光谱非常相似。它可以使我们得出结论,猪软骨可以代替人软骨用于体内研究。借助于光传输方程的一维扩散近似解来处理获得的数据。通过迭代比较人和猪软骨的T $ -t $ /,R $ -t $ /和T $ -a $ /值,我们发现了散射系数s,吸收系数k和散射各向异性系数g。我们特别发现,对于500 nm辐照,s等于37.6正负3.5 cm $ + $ MIN @ 1 $ /,g等于0.56正负0.05,k大约等于0.5正负0.3 cm $ + $ MIN @ 1 $ /。以上数据在蒙特卡洛模拟中用于软骨样品散射光的空间强度分布。计算出的轮廓与使用光学多通道分析仪(OMA)测量的轮廓非常相似。 !6

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