Airway Smooth Muscle Modulates Airway Inflammation in Asthma

摘要

Airway smooth muscle (ASM) plays a central role in regulating bronchomotor tone in asthma; however, ASM may also orchestrate and perpetuate airway inflammation by promoting recruitment, activation and trafficking of inflammatory cells in the airways. This review addresses the immunomodulatory function of ASM and highlights how such function may have therapeutic implications in the management of asthma.