The After-Hyperpolarization Amplitude and the Rise Time Constant of IPSC Affect the Synchronization Properties of Networks of Inhibitory Interneurons

摘要

The Fast Spiking (FS) intemeurons are coupled by both electrical and inhibitory synapses and experimental findings suggest that they operate as a clockwork affecting the processing of neural information. At present, it is not known which is the functional role of electrical synapses in a network of inhibitory intemeurons. In our contribution, by using a single compartment biophysical model of an FS cell, we determine the parameter values leading to the emergence of synchronous regimes in a network of FS intemeurons coupled by chemical and electrical synapses. We also compare our results with those recently obtained for a pair of coupled Integrate & Fire neural models.