Porous Scaffold of n-HA/PA66/CS for Tissue Regeneration

摘要

Nano-hydroxyapatite/polyamide66/chitosan composite (n-HA/PA66/CS) was prepared by a co-precipitation method and porous scaffolds from n-HA/PA66/CS composite were prepared by means of porogen-leaching method and were characterized by SEM, IR, XRD and universal mechanical testing machine. IR and XRD analyses showed that some chemical bonds existed between n-HA and polymers. Furthermore, macroporous structure of the scaffolds and mechanical strength were tested with a changed ratio of porogens (PVP/NaCl). When the ratio of PVP and NaCl isl: 6, the scaffold processed highly porosity and the pores were interconnected. The compressive strength of the scaffold, can meet the requirement of tissue regeneration.