CELLULOSE MATERIALS MODIFIED BY ANTISEPTICS AND THEIR ANTIMICROBIAL PROPERTIES

摘要

Adsorption properties of dressing cellulose materials with respect to surfactant antiseptics were studied. The antiseptics is a complex of the copolymer of N-vinypyrrolidone and crotonic acid with dimethilbenzylammonium chloride (a synthetic polymer with spectrum of antimicrobial effect) and its low molecular weight analogue (dimethilbenzylammonium chloride). It was established that cellulose materials reversibly adsorb mentioned surfactant antiseptics depending on their concentration in the initial solution. Maximum release of surfactant antiseptics is achieved at solution at pH=7.0. Microbiological tests of cellulose materials modified by antiseptics have shown that they exhibit antimicrobial activity. These results can be used in medical practice in clinics for imparting antimicrobial properties dressing materials.