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Determining the Threshold of Radiotherapy Delivery Error Detection Using Delta4

机译:使用Delta4确定放射治疗传递错误检测的阈值

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Intensity Modulated Radiation Therapy and Volume Modulated Arc Therapy are now widely used in cancer treatment, but due to their complex nature each clinical plan is verified before applying on patient. Many different verification systems are available for this purpose, but because there is no regulation that would make it an obligatory, manufacturers usually don't give such information as devices error detection threshold, repeatability etc. Therefore clinics must carry out tests before using these devices. This article is dedicated to the determining of IMRT/VMAT plan verification systems Delta4 (Scandidos, Uppsala, Sweden) error detection threshold. 10 Head & Neck IMRT and 5 esophagus VMAT clinical plans were modified with intentionally introduced errors and then verified on Delta4. Positioning errors for various moving parts (MIX, Jaws, Collimator and Gantry) together with dose related errors (MU, missing control points) were tested. The resulting gamma index was compared to the one from unmodified plan. A clear detection threshold for IMRT was detected for shift, MU, Jaws, collimator and gantry errors and for VMAT for MU and Jaws errors. No clear error detection threshold within tested error size range was found for the rest of the introduced errors.
机译:调强放射疗法和体积调变电弧疗法目前已广泛用于癌症治疗,但是由于其复杂性,每个临床计划在应用于患者之前都要经过验证。为此,可以使用许多不同的验证系统,但是由于没有强制性的法规,制造商通常不会提供诸如设备错误检测阈值,可重复性等信息。因此,在使用这些设备之前,诊所必须进行测试。本文致力于确定IMRT / VMAT计划验证系统Delta4(Scandidos,乌普萨拉,瑞典)错误检测阈值。修改了10个Head&Neck IMRT和5个食道VMAT临床计划,并故意引入了错误,然后在Delta4上进行了验证。测试了各种运动部件(MIX,钳口,准直仪和龙门架)的定位误差以及与剂量相关的误差(MU,缺少控制点)。将所得的伽玛指数与未经修改的计划的伽玛指数进行比较。已针对班轮,MU,钳口,准直仪和龙门误差以及IM和MU和钳口误差的VMAT检测到IMRT的清晰检测阈值。对于其余引入的错误,未在测试的错误大小范围内找到明确的错误检测阈值。

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