This paper presents a framework for considering the relationship between biological computation and unconventional computation. The paper first considers several standard views of computation. Next it outlines what motivates our interest in unconventional computation and how our view of computation can be extended. Biomolecular and biological computation are compared and contrasted, with particular attention to recent work on smart proteins, fuzzy enzymes and computational tissues. Finally a generic decomposition of unconventional computing systems is discussed, along with the properties of their parts.
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