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A design of a drug driver system for controlling an insulin pump and microcontroller hardware implementation using two-point calibration algorithm

机译:使用两点校准算法控制胰岛素泵的药物驱动器系统设计和微控制器硬件实现

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The study covered a drug driver system that can be used for continuous glucose monitoring system intended to drive a pump that will administer insulin for the purpose of combating diabetes. The system begins with a microcontroller unit having an analog voltage input that is derived from a calibrated linearity curve relative to that of glucose concentration, the microcontroller algorithm processes the data and determines whether an output of insulin or glucagon is needed. The output of the microcontroller unit is a time variable pulse which is dependent on the glucose concentration reading. Separately, a full custom IC design is conducted for an actual drug driver circuit for the purpose of miniaturization to make the system viable for implantation. The hardware test for the microcontroller unit indicates that the algorithm can be used to properly read glucose concentrations and provide an output accordingly. However, there are delays within the microcontroller which affect the response of the output. For the full custom IC design of the drug driver circuit, it is observed that the parasitic capacitances and resistances affect the propagation delay and power dissipation of the circuit but can still be used in a drug driver system.
机译:这项研究涵盖了一种药物驱动器系统,该系统可用于连续葡萄糖监测系统,该系统旨在驱动泵来管理胰岛素,以抗击糖尿病。该系统从具有模拟电压输入的微控制器单元开始,该模拟电压输入是从相对于葡萄糖浓度的校准线性曲线得出的,微控制器算法处理该数据并确定是否需要胰岛素或胰高血糖素的输出。微控制器单元的输出是随葡萄糖浓度读数而变化的时变脉冲。单独地,针对实际的药物驱动器电路进行了完全定制的IC设计,目的是使其小型化,从而使该系统可用于植入。对微控制器单元的硬件测试表明,该算法可用于正确读取葡萄糖浓度并相应地提供输出。但是,微控制器内部存在一些延迟,这些延迟会影响输出的响应。对于药物驱动器电路的完全定制IC设计,可以观察到寄生电容和寄生电阻会影响电路的传播延迟和功耗,但仍可以在药物驱动器系统中使用。

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