Research on the Influence of Impedance Distribution on Equivalent Electric Dipole Localization in Head Texture

摘要

EEG IP has unique advantages in brain function research, cognition research and brain disease detection. Equivalent dipole localization is a brain electrical source localization method widely used in electroencephalogram inverse problem (EEG IP). In order to clarify the influence of electrical conductivity distribution in EEG IP, four-layer sphere model was constructed in this paper. The analysis solution of its surface voltage was concluded through mirror method and it was verified by calculation with FEM software. Equivalent dipole localization was worked out by using Sequential Quadratic Programming (SQP), and the main issue was studied as following: the influence of equivalent dipole localization when the eccentric sphere with high electrical conductivity exists. The emulation result proves that the electrical conductivity of unique part of head tissues has significant influence on equivalent dipole localization while much less influence on its intensity estimation.