Results for sulfate-reducing bacteria and products of their metabolism, as flotation regulators of sulfide minerals and ores, and solvents of antimony-and tin-containing concentrates are presented. Bacteria act as sulfidizers and depressants in flotation, and desorbents of sulfhydril collectors from surfaces of minerals. Galena, chalcopyrite, sphalerite, pyrite and antimonite are more effectively depressed by microorganisms in contrast with Na_2S. Separations of galena from sphalerite, molybdenite from chalcopyrite are realized by a selective bacterial desorption of xanthogenate. Frequency of rotating spin-marked reagents sorbed on cerussite, processed with sulphate-reducing bacteria, reveals more "hard" fastening of radical. Purification of industrial effluents from heavy metal ions by bacteria is shown. Problems of sulfate containing mine waters, are reviewed considering the action of the solar energy and catalyzers to produce hydrogen fuel and sulphur
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