Interferometer immunosensor based on porous silicon for determining alpha-fetoprotein

摘要

An increased level of alpha-fetoprotein ( AFP) in the blood may be a sign of liver cancer. Porous silicon based optical microcavities structure is prepared as a label-free immunosensor platform for detecting AFP. After the antigen-antibody reaction, it is monitored that the red shift of the reflection spectrum of the immunosensor increases with the antigen concentration. This research also plays a potential role for the extensive applications in immunoassay.