Application of photodynamic fluorescence diagnosis in skin tumors

摘要

Photodynamic fluorescence diagnosis ( PDD ) is a technology that use laser-induced fluorescence in the presence of photosensitizer to diagnose tumor. This application can help locate the extent of tumor and the edge of tumor lesion and is very important for the treatment of the tumor. PDD plays an important guiding role in accurately grasping the changes of photosensitizer information in the target tissue, understanding the progress of photodynamic therapy, and establishing a reasonable photodynamic therapy (PDT) program. A brief overview of the principles of fluorescence diagnostics is talked about here. And through experiments, it has obtained fluorescence before and after the treatment in several skin tumors, such as basal cell carcinoma (BCC) and Extramammary Paget's disease.