Porosity and Computational Flow Analysis for Collagen-membrane and Cross-Linked Gelatin Scaffolds using ahigh contrast MicroCT with submicron resolution

摘要

The current study is focused on developing a rapid 3D imaging technique to characterize porosity and fluid dynamics in collagen membrane and cross-linked gelatin composite scaffolds for tissue regeneration. Fluid dynamic transport properties, namely porosity and permeability, are a main topic for bioresorbable scaffolds, designed to permit diffusion of oxygen and nutrients in depth, rapid and physiological colonization by cultured cells, production of extra-cellular matrix while biodegradation occurs.