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High-resolution grating interferometer for phase-contrast imaging at PETRA Ⅲ

机译:用于PETRAⅢ相衬成像的高分辨率光栅干涉仪

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Phase-contrast imaging has proven to be a valuable tool when investigating weak absorbing materials like soft tissue, due to its increased contrast compared to conventional absorption-contrast imaging. While propagation-based phase-contrast is an ideal tool to achieve highest resolution at a good contrast for almost not-absorbing material, it quickly comes to its limitations on applications demanding for a high dynamic range in contrast. For those applications grating-based phase-contrast is the tool of choice, although it lacks of spatial resolution compared to inline phase-contrast or attenuation-based microCT. To reduce this gap in spatial resolution we equipped the two PETRA Ⅲ beamlines P05 and P07 with a customized set of mechanics to maximize the performance of the interferometer. After latest optimization steps our system allows for phase-contrast measurements in a continuous energy range between 10 keV and 80 keV. Dependent on investigated material and energy the setup is capable to achieve a spatial resolution of 5 μm on a field of view of 6.5 mm. We will present our implementation of grating-based phase-contrast computed tomography for fast and high-resolution measurements at the PETRA Ⅲ along with its recent optimization, and demonstrate its performance based on different kinds of applications.
机译:当研究弱吸收材料(如软组织)时,相衬成像已被证明是一种有价值的工具,因为与常规的吸收对比成像相比,相衬成像具有更高的对比度。尽管基于传播的相衬是在几乎不吸收材料的情况下以良好的对比度实现高分辨率的理想工具,但它很快就受到要求高动态范围的应用的限制。对于那些应用,基于光栅的相位对比是首选工具,尽管与在线相位对比或基于衰减的microCT相比,它缺乏空间分辨率。为了缩小空间分辨率的差距,我们为两条PETRAⅢ光束线P05和P07配备了一套定制的机械装置,以最大限度地提高干涉仪的性能。经过最新的优化步骤后,我们的系统允许在10 keV至80 keV的连续能量范围内进行相衬测量。根据所研究的材料和能量,该装置能够在6.5 mm的视场上实现5μm的空间分辨率。我们将介绍在PETRAⅢ上用于快速和高分辨率测量的基于光栅的相差计算机断层扫描技术及其最新的优化方法,并根据不同的应用场合展示其性能。

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