首页> 外文会议>Controlled Release Society 31st annual meeting transactions: abstracts >New Bi-Component Fibers Capable of Releasing Growth Factors and Viruses with Retained Biological Activity
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New Bi-Component Fibers Capable of Releasing Growth Factors and Viruses with Retained Biological Activity

机译:能够释放具有保留的生物活性的生长因子和病毒的新型双组分纤维

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摘要

Bi-component fibers consisting of a hydrogelrninterior encased within a PLLA sheath have beenrnshown to release drugs with a zeroth orderrnrelease kinetics. We have measured both proteinrnrelease as well as the release of beta-galactosernadenovirus both in vitro and in vivo in a mousernpancreatic tumor model.
机译:已经显示出由包裹在PLLA鞘内的水凝胶内部构成的双组分纤维可以释放具有零级释放动力学的药物。我们已经在小鼠胰腺肿瘤模型中测量了体内和体外的蛋白释放以及β-半乳糖核糖核酸病毒的释放。

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