Adsorption of Poloxamers onto Polymerised Liposomes enhances Intranasal Immune Response toTetanus Toxoid

摘要

Poloxamer coating of polymerised liposomes wasshown to be higher with L121 than L101. Tetanus toxoid(TT) adsorption was lower to poloxamer -coated liposomesthan to non -modified liposomes. L101 or L1 21 coatedpolymerised liposomes evoked a higher anti -TT IgGimmune response compared to non -modified polymerisedliposomes after intranasal administration.