Laser detoxication of acute poisonings with carbon monoxide

摘要

A series of model experiments have been carried out. Those experiments have proved the fact of laser- induced ptotodissociation of HbCO using Nd-YAG-laser with wavelength 533 nm at different conditions. Spontaneous reassociation of ligand to hemoproteid has been observed during the interpulse period. In order to prevent the reversibility of the reaction some oxidizing substances as well as trap-like functioning agents have been tested. The preliminary results allow us to propose the application oi nonreversible laser-induced HbCO photodissotiation in the capacity of new physical method to treat acute carbon monoxide poisoning.