Oxygen saturation dependent absorption and scattering of whole blood

摘要

We report on the scattering properties of oxygenated and de-oxygenated whole blood from 250-1000 nm. We determined the complex refractive index of oxygenated and de-oxygenated hemoglobin using Kramers Kronig analysis and Optical Coherence Tomography measurements. Combining these data with Mie theory, the scattering properties of oxygenated and deoxygenated whole blood were calculated. The results show strong oxygen saturation dependent scattering effects, which should be taken into account in data analysis of optical oxymetry.