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Fourier Domain Mode Locked (FDML) lasers at 1050 nm and 202,000 sweeps per second for OCT retinal imaging

机译:1050 nm和每秒202,000次扫描的傅立叶域锁模(FDML)激光,用于OCT视网膜成像

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摘要

Retinal imaging ranks amongst the most important clinical applications for optical coherence tomography (OCT) . The recent demonstration of increased sensitivity in Fourier Domain detection has opened the way for dramatically higher imaging speeds, up to axial scan rates of several tens of kilohertz. However, these imaging speeds are still not sufficient for high density 3D datasets and a further increase to several hundreds of kilohertz is necessary. In this paper we demonstrate a swept laser source at 1050 nm with a sweep rate of 202 kHz. The laser source provides ~10 mW average output power, up to 60 nm total sweep range and a sensitivity roll off of less than 10 dB over 4 mm. In vivo 2D and 3D imaging of the human retina at a record axial scan rate of 101 kHz is demonstrated. These results suggest that swept source OCT has the potential to significantly outperform spectral/Fourier domain OCT for ophthalmic imaging applications in the future.
机译:视网膜成像是光学相干断层扫描(OCT)的最重要的临床应用之一。最近在傅立叶域检测中提高灵敏度的证明为显着提高成像速度开辟了道路,其轴向扫描速率高达几十千赫兹。但是,这些成像速度对于高密度3D数据集仍然不够,因此有必要进一步提高到几百千赫兹。在本文中,我们演示了在1050 nm处具有202 kHz扫描速率的扫频激光源。激光源提供约10 mW的平均输出功率,高达60 nm的总扫描范围以及在4 mm的范围内低于10 dB的灵敏度滚降。已证明以101 kHz的轴向轴向扫描速率对人视网膜进行体内2D和3D成像。这些结果表明,在未来的眼科成像应用中,扫频光源OCT可能会大大胜过光谱/傅立叶域OCT。

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