Central Blood Pressure Waves Assessment: A Validation Study of Non-Invasive Aortic Pressure Measurement in Human Beings

摘要

Measurement of central systolic (aortic) blood pressure has been shown to provide the more precise information to evaluate target organ assessment. However, non-invasive central blood pressure measurement procedures are still under analysis. The aim of this study was to compare pressure waveforms invasively obtained in the aorta, with the corresponding waveforms non-invasively recorded using a Mobil-O-Graph device. In this research were included 20 subjects submitted for invasive coronary evaluations. They were 10 males (68±12 y. o., BMI: 27.4±4.6Kg/m2) and 10 females (77±8 y. o., BMI: 28.5±5.3Kg/m2). During the invasive aortic pressure recording a synchronized non-invasive Mobil O Graph acquisition beat by beat was performed. Both blood pressure waves were digitized and stored for sub-sequent analysis and calculations. A computerized inter-polation procedure was developed in our laboratory to compare invasive and non-invasive central blood pressure waves. A significant correlation between Mobil O Graph central blood pressure measurements and the corresponding invasive values, was found in men (r收起