Silver doped nanomaterials and their possible use for antibacterial photodynamic activity

摘要

Bacteria, viruses and parasites elimination from human environment is one of the most important problem, extensively studied by many groups. The growing resistance to commonly used disinfection and/or sterilization methods and antibiotics, is one of the major problem in the health care sector. Nanomaterials with tailored antimicrobial features may find applications in this field. One of the promising application of nanomaterials is the possibility to enhance the antimicrobial photodynamic therapy (APDT), which combines a nontoxic photoactive dye - photosensitizer and nanomaterials properties. This paper focused on the examination of optical and antibacterial properties of silica- and titania-based nanopowders doped with silver and photosensitizer - Photolon. Various concentration of Photolon and nanomaterials have been prepared in order to examine the fluorescence enhancement and resulting better antibacterial activity. It was proved that the fluorescence intensity of Photolon increased, depending on silver concentration. Antibacterial study showed that silver doped silica and titania nanoparticles revealed antibacterial activity, but in the presence of Photolon, the antibacterial activity of materials is more effective.