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Modeling Protein Interaction Networks with Answer Set Programming

机译:用答案集编程对蛋白质相互作用网络建模

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In this paper we propose the use of answer set programming (ASP) to model protein interaction networks. We argue that this declarative formalism rivals the popular boolean networks in terms of ease of use, while at the same time being more expressive. As we demonstrate for the particularcase of a fission yeast network, all information present in a boolean network, as well as relevant background assumptions,can be expressed explicitly in an answer set program. Moreover, readily available answer set solvers can then be used to find the stable states of the network.
机译:在本文中,我们建议使用答案集编程(ASP)来建模蛋白质相互作用网络。我们认为,这种声明形式主义在易用性方面可以与流行的布尔型网络相媲美,而同时却更具表现力。正如我们针对裂变酵母网络的特殊情况所展示的那样,布尔网络中存在的所有信息以及相关的背景假设都可以在答案集程序中明确表达。此外,然后可以使用随时可用的答案集求解器来查找网络的稳定状态。

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