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Biologically Inspired Classifier

机译:生物启发分类器

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摘要

We present a method for measuring the distance among records based on the correlations of data stored in the corresponding database entries. The original method (F. Bagnoli, A. Berrones and F. Franci. Physica A 332 (2004) 509-518) was formulated in the context of opinion formation. The opinions expressed over a set of topic originate a "knowledge network" among individuals, where two individuals are nearer the more similar their expressed opinions are. Assuming that individuals' opinions are stored in a database, the authors show that it is possible to anticipate an opinion using the correlations in the database. This corresponds to approximating the overlap between the tastes of two individuals with the correlations of their expressed opinions.rnIn this paper we extend this model to nonlinear matching functions, inspired by biological problems such as microarray (probe-sample pairing). We investigate numerically the error between the correlation and the overlap matrix for eight sequences of reference with random probes. Results show that this method is particularly robust for detecting similarities in the presence of traslocations.
机译:我们提出了一种基于存储在相应数据库条目中的数据的相关性来测量记录之间距离的方法。原始方法(F. Bagnoli,A。Berrones和F. Franci。Physica A 332(2004)509-518)是在舆论形成的背景下制定的。在一组主题上表达的观点在个人之间建立了一个“知识网络”,其中两个个体之间的距离越近,他们表达的观点越相似。假设个人的意见存储在数据库中,作者表明可以使用数据库中的相关性来预测意见。这对应于用表达的意见的相关性来近似两个人的口味之间的重叠。在本文中,我们将这种模型扩展到非线性匹配函数,这是受诸如芯片(探针-样品配对)等生物学问题的启发。我们用随机探针在数字上研究了八个参考序列的相关性和重叠矩阵之间的误差。结果表明,该方法对于在易位情况下检测相似性特别可靠。

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