OPTICAL-THERMAL RESPONSE AND DYNAMIC THERMAL DAMAGE OF BIO-TISSUE DURING LASER THERMOTHERAPY

摘要

Laser thermotherapy is a technique used for tumor treatment. It generates a local heating, causes thermal coagulation of living tissue and eliminates the tumor. Precise heating of tumor tissue with healthy minimum thermal injury to adjacent tissue is essential to thermotherapy. Understanding of heat transfer and optical-thermal interaction is important for control of temperature and design of thermotherapy. This study applies the Arrhenius damage model to describe the heat-induced change of optical properties. It calculates the distribution temperature, damage and optical-thermal response of bio-tissue during the laser treatment, and shows how these factors affect the effectiveness of laser thermotherapy. Similar research has been performed by Kim and coworkers [1996], lizuka and coworkers [2000], and Whelan and coworkers [2000]. This study relaxes some conditions in previous investigations. It reveals the importance and the effect of size of the laser head.