Fabrication of Scaffold-Free Engineered Cartilage Using Passaged Chondrocytes in the presence of Insuline Like Growth Factor 1 (IGF-1)

摘要

Two passaged (P2) immature porcine articular chondrocytes were used to fabricate an engineered cartilage tissue in an in vitro scaffold-free system with or without insulin like growth factor 1 (IGF-1). This study shows the possibility of the fabrication of structurally regular neo-cartilage tissue using passaged chondrocytes in the scaffold-free system with insulin like growth factor-1 (IGF-1).