Gamma-Frequency Synaptic Input Enhances Gain Modulation of the Layer V Pyramidal Neuron Model

摘要

Cortical gamma frequency (30-80 Hz) oscillations have been suggested to underlie many aspects of cognitive functions. In this paper we compare the/ — / curves modulated by gamma-frequency-modulated stimulus and Poisson synaptic input at distal dendrites of a layer V pyramidal neuron model. The results show that gamma-frequency distal input amplifies the sensitivity of neural response to basal input, and enhances gain modulation of the neuron.