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Studies of Pathogenecity Islands in Escherichia coli O157:H7

机译:大肠杆菌O157:H7的致病岛研究

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摘要

The pathogenicity islands (PAIs) have been defined for many strains of Pathogenic bacteria. Typically, these sequences are large (.30-kb) blocks of DNA inserted within or near tRNA genes, contain direct repeats and insertion sequences, have a GC content that differs from that of the rest of the genome, and encode defined virulence determinants. It is believed that the pathogenecity islands may be responsible for the emerging pathogenic bacterial species. The most common cause of urinary tract infection (UTI) uropathogenic strains of E.
机译:已经为许多致病菌菌株定义了致病岛(PAI)。通常,这些序列是在tRNA基因内或附近插入的大(.30-kb)DNA块,包含直接重复序列和插入序列,GC含量不同于基因组其余部分,并编码确定的毒力决定簇。据认为,致病岛可能是造成新出现的致病细菌的原因。尿路感染(UTI)尿路致病性大肠杆菌的最常见原因。

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