MELATONIN LIMITS EXPERIMENTALLY INDUCED CYCLOSPORINE A NEPHROTOXICITY

摘要

Our findings showed that melatonin administration reduced almost completely severe nephrotoxicity induced by prolonged CsA treatment. These data agree with favourable functional parameters recently reported after melatonin plus CsA short-term treatment in rats (4). Further studies are necessary to test if melatonin could be effective also in humans.