MODELLING THE CIRCULATION IN THE MAMMALIAN LENS

摘要

The ocular lens generates an internal circulation in order to transport nutrients into the lens. The internal circulation enters at the poles and exits at the equator of the lens. This internal circulation is the result of the localization of membrane proteins and the cellular architecture of the lens. This work presents the development of a finite element model that solves the advection-diffusion equations for ion fluxes, the isotonic transport equations for water flux and the equations for transmembrane ion and water fluxes.