Simulation of Flow Dynamics in Left Main Coronary Bifurcation On Different Situation of Blood Viscosity

摘要

Left main coronary arterial model was made by digitalrnsubtraction and novel 3D reconstruction methods analyzedrnfrom coronary angiography data base. Inlet flow velocityrnwaveform of the pulsatile flow obtained from in vivornintravascular Doppler ultrasound flow data. In vivo pressurernprofile was adopted also. For attaining effective numericalrnanalysis of hemodynamics, we used finite volume method,rnadapting Rhie-Chow algorithm. The governing equations arerncalculated under a non-staggered grid system. We calculatedrnall the profile of flow patterns, wall shear stress, and particlernresidence time during one cardiac cycle according asrnvarying blood viscosity. During the cardiac cycle, coronaryrnflow phases are classified as accelerated and deceleratedrnphase. The flow separation and secondary flow around thernbifurcation area is more significant on deceleration phase.rnThe profiles of wall shear stress are more separated onrndeceleration phase, also. And these patterns are morernprominent when the blood viscosity is increased.rnFurthermore, higher blood viscosity, more increased thernparticle residence time. Considering the design of microrobotrnfor interventional usage of coronary aterial disease, wernsuggest that it is essential to understand the flow dynamicsrnin coronary arterial trees.