Towards Biocompatible Medical Devices: Modification of Polymer and Metal Surfaces

摘要

In order to prepare new materials for medical devices the plasma technology enables chemical reactions on biomedical surfaces, like polymers or metals. Functionalization with adhesion factors based on RGD it will be possible to seed cells on surfaces. Avoiding of a copper-mediated click reaction reduces the hazard of remaining toxic compounds on the surface. The biological evaluation showed that this approach leads to a dense cell layer. New approaches are tested to varify the applications of this method.