PROCESSING OF BIOACTIVE CERAMICS WITH DEFINED POROSITY

摘要

The current medical procedure for the fixation and stabilization of damaged bones requires the insertion and later removal of metallic pens and plates. Such a procedure damages healthy tissue and is time consuming and expensive. While there are materials that chemically bond to tissue and resorb after their usefulness, their use for fixation has been impossible because of their low mechanical strength. A new processing method shows the ability to create bone scaffolds with a mixture of chemical reactivity, functional microstructure, and good mechanical properties. This processing method uses the phase separation between polymers of two compositions to create large pores. This scaffold is a composite of sol-gel produced bioglass and a reinforcing polymer for bioactivity, resorbablity, and strength. The scaffold has a microstructure of interconnected porosity for high surface area and the possibility of integrating bone growth factors or bone cells to accelerate the repair of damaged tissue.