Development of a phototherapy system with a pulse oximetry module as an element for tissue oxygen measurement

摘要

Photodynamic therapy is a type of phototherapy that involves the administration of a photosensitizer drug followed by a local illumination with light of specific wavelength. In the presence of oxygen molecules, the light illumination of photosensitizer can activate the production of reactive oxygen species which yield the death of target cells. In order to obtain the best therapy response, it can be measured the oxygen tissue concentration to adjust the initial parameters of the treatment. In this work it is presented an irradiation system which allows the application of radiation at wavelengths 450, 523, 630 nm using as a light sources, power-controlled light emitting diodes besides a module to measure the tissue oxygen saturation based on pulse oximetry.