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RATIOMETRIC LASER-INDUCED FLUORESCENCE (LIF) THERMOGRAPHY OF RADIOFREQUENCY HEATED TISSUE PHANTOMS

机译:放射频率加热的组织幻像的激光诱导荧光(LIF)热成像

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摘要

A ratiometric laser-induced fluorescence (LIF) thermographic method has been developed to quantify the temperature fields associated with radiofrequency (RF) heating probes used to treat joint instabilities associated with the shoulder, knee, and ankle. Accurate temperature field measurements in tissue phantoms represent invaluable data for the purpose of developing and verifying computer models of tissue heating. Measuring temperature fields associated with RF probe heating in physiological environments poses problems for traditional methods. Thermocouples, infrared thermometry and fluoroptic methods are limited due to inability of thermocouples to operate in an RF environment, the opaque nature of physiological solutions to IR wavelengths and the relatively large size of optical fibers used in fluoroptic thermometry respectively. Whole field temperature mapping and heat flux measurements around monopolar and bipolar radiofrequency (RF) probes have been performed in tissue phantoms using two-color laser induced fluorescence (LIF) and the ratio of the fluorescent emission intensities of Rhodamine B and Rhodamine 110. The method is described, the operating characteristics are defined and examples of the application of the method to radiofrequency (RF) heating in phantom tissues are included.
机译:已经开发出一种比例激光诱导荧光(LIF)热成像方法来量化与射频(RF)加热探头相关的温度场,该探头用于治疗与肩膀,膝盖和脚踝相关的关节不稳。组织体模中准确的温度场测量代表了宝贵的数据,可用于开发和验证组织加热的计算机模型。在生理环境中测量与RF探针加热相关的温度场给传统方法带来了问题。由于热电偶无法在RF环境中运行,生理溶液对IR波长的不透明性以及分别用于荧光光度法的较大尺寸的光纤,热电偶,红外温度法和荧光法受到了限制。使用双色激光诱导荧光(LIF)以及罗丹明B和罗丹明110的荧光发射强度之比,已在组织体模中进行了围绕单极和双极射频(RF)探针的全场温度映射和热通量测量。该方法进行了描述,定义了操作特性,并包括了将该方法应用于幻像组织中的射频(RF)加热的示例。

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