Enantioselective Separation on a Chiral Stationary Phase of Polysaccharide with 3,5-Dimethylphenylcarbamate Prepareded by ATRP

摘要

1.Introduction Polysaccharide derivatives coating onto silica matrices represents nowadays one of the most popular chiral stationary phases (CSPs) and these kinds of phases are commercially available [1-2]. However, the solubility of polysaccharide derivatives in a number of solvents limits the application range on the commercial chiral columns. This problem can be solved by chemically fixing polysaccharide derivatives onto silica matrices. Chemically bonded cellulose and amylose phenyicarbamate-based CSPs have been prepared by radical polymerization, radical co-polymerization reaction, and etc. By many researchers [3-5] On the one hand, atom transfer radical polymerization (ATRP) technique is very efficient for grafting from solid surfaces. Also, ATRP allows better control over the molecular weight and distribution of the target polymer, much attention has been paid to the use of this polymerization method in the synthesis of polymer brushes from a surface [6-7].