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Validation of a Finite Element Method framework for cardiac mechanics applications

机译:用于心脏力学应用的有限元方法框架的验证

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Modeling cardiac mechanics is a particularly challenging task, mainly because of the poor understanding of the underlying physiology, the lack of observability and the complexity of the mechanical properties of myocardial tissues. The choice of cardiac mechanic solvers, especially, implies several difficulties, notably due to the potential instability arising from the nonlinearities inherent to the large deformation framework. Furthermore, the verification of the obtained simulations is a difficult task because there is no analytic solutions for these kinds of problems. Hence, the objective of this work is to provide a quantitative verification of a cardiac mechanics implementation based on two published benchmark problems. The first problem consists in deforming a bar whereas the second problem concerns the inflation of a truncated ellipsoid-shaped ventricle, both in the steady state case. Simulations were obtained by using the finite element software GETFEM++. Results were compared to the consensus solution published by 11 groups and the proposed solutions were indistinguishable. The validation of the proposed mechanical model implementation is an important step toward the proposition of a global model of cardiac electro-mechanical activity.
机译:对心脏力学进行建模是一项特别具有挑战性的任务,这主要是由于对基本生理学的了解不足,缺乏可观察性以及心肌组织机械特性的复杂性。心脏机械解算器的选择尤其会带来一些困难,特别是由于大变形框架固有的非线性可能会导致潜在的不稳定性。此外,对所获得的仿真进行验证是一项艰巨的任务,因为没有针对此类问题的解析解决方案。因此,这项工作的目的是基于两个已发布的基准问题提供对心脏力学实施方案的定量验证。第一个问题在于杆的变形,而第二个问题涉及在稳态情况下均被截断的椭圆形心室的膨胀。通过使用有限元软件GETFEM ++获得了仿真。将结果与11个小组发布的共识解决方案进行了比较,所提出的解决方案没有区别。提出的机械模型实现的验证是迈向心脏电动机械活动全局模型的重要一步。

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