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Adaptive control solution for T1DM control

机译:T1DM控制的自适应控制解决方案

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摘要

The “Type 1 Diabetes Mellitus (T1DM)” is a dangerous illness that concerns yearly increasing population. The control of the glucose level in the human body is a widely investigated subject area that also has serious technical difficulties as the lack of reliable system model for each individual patient, the limitations regarding the observability of the complete internal state of the patient (at least in the view of the system model). On this reason the “Model Predictive Control (MPC)” needs either robust or adaptive completion in this field of application. In the lack of observable data the traditional state estimators may have only limited relevance. The “Robust Fixed Point Transformation (RFPT)” based method was elaborated for the design of adaptive controllers typically for such situations. It does not need any sophisticated system model, it can work on the basis of observations that concern only the controlled quantity without the need of complete state estimation. In the present paper the use of the RFPT-based adaptive controller is reported in simulation investigations in which the validity of Bergman's “Minimal Model” is assumed. Promising simulation results are presented.
机译:“ 1型糖尿病(T1DM)”是一种危险疾病,涉及不断增长的人口。人体中葡萄糖水平的控制是一个被广泛研究的主题领域,由于缺乏针对每个患者的可靠系统模型,关于患者完整内部状态的可观察性的限制(至少在系统模型的角度来看)。因此,在该应用领域中,“模型预测控制(MPC)”需要鲁棒或自适应完成。在缺乏可观察数据的情况下,传统状态估计器的相关性可能有限。精心设计了基于“鲁棒定点变换(RFPT)”的方法,用于设计通常用于此类情况的自适应控制器。它不需要任何复杂的系统模型,它可以在仅涉及受控量的观察结果的基础上工作,而无需进行完整的状态估计。在本文中,在模拟研究中报告了基于RFPT的自适应控制器的使用,其中假定了伯格曼“最小模型”的有效性。提出了有希望的仿真结果。

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