Intensified Liquid/Liquid Mass Transfer in Corning~? Advanced-Flow? Reactors

摘要

Corning~? Advanced-Flow? reactors are continuous flow reactors with hydraulicrndiameters in the range of 0.3 up to few millimetres. These devices make possible thernswitch of chemical reactions from batch mode to continuous processing through morernefficient, more economical and safer processes. In addition, they provide a platform forrndeveloping innovative chemistries that have never been considered industriallyrnpractical, either for high exothermicity, hazard or yield reasons.rnCorning proprietary apparatuses are compact, adaptable and scalable, optimizing thernoverall production cost and quality of high-value specialty, fine, and pharmaceuticalrnchemicals.rnThis paper presents the mixing of immiscible liquids in fluidic modules devoted to lowrnflow applications in laboratory studies. The degree of mixing is quantified throughrnextraction efficiency measurements at organic/aqueous phase ratios of 0.25. Thernsatisfactory high extraction efficiency, which was superior to 0.8, indicates Corning~?-rnAdvanced Flow ReactorsTM as efficient tools, providing good characteristics forrnmultiphase applications.