Anti-proprotein converting enzyme subtilisin kexin type 9 (anti-PCSK9) compound and methods of using it for the treatment and / or prevention of cardiovascular disease

摘要

Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for use of such compounds to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.